Italy is a dream destination filled with history, romance, world-class cuisine, and breathtaking landscapes. Whether it’s your first time or your tenth, this 10-day itinerary will take you through Italy’s most iconic cities—Rome, Florence, Venice, and Milan—while leaving room for unforgettable experiences.
Day 1-3: Rome – The Eternal City
Day 1: Arrival & Ancient Rome
Start your adventure in Rome, the capital of Italy and a city brimming with ancient wonders. Upon arrival at Leonardo da Vinci International Airport (FCO), check into your centrally located hotel. After settling in, head to the Colosseum, an awe-inspiring amphitheater where gladiators once fought. Walk through the Roman Forum, the heart of ancient Rome’s political and social life, and climb up to Palatine Hill, one of Rome’s seven hills, offering stunning views. For lunch, enjoy a classic Roman dish such as Cacio e Pepe or Carbonara at a local trattoria. In the afternoon, visit the Pantheon, a marvel of Roman engineering with its impressive domed ceiling. Toss a coin into the Trevi Fountain to ensure your return to Rome before strolling through Piazza Navona, a lively square known for its stunning Baroque fountains and vibrant street performers.
Day 2: Vatican City & Trastevere
Begin your day at St. Peter’s Basilica, the largest church in the world, where you can admire Michelangelo’s Pietà and climb to the dome for panoramic views of Rome. Next, explore the Vatican Museums, home to an extensive art collection, culminating in the breathtaking Sistine Chapel, where you can marvel at Michelangelo’s frescoes. After a morning of art and history, cross the Tiber River to the charming neighborhood of Trastevere, known for its cobblestone streets and traditional Roman atmosphere. Enjoy a leisurely lunch at a family-run trattoria, followed by a visit to Santa Maria in Trastevere, one of Rome’s oldest churches adorned with beautiful mosaics. End your day with a scenic sunset view at Gianicolo Hill, one of the best panoramic spots in the city.
Day 3: Hidden Gems & Departure to Florence
Start your morning by exploring Campo de’ Fiori, a bustling market where you can sample local delicacies. Walk through the historic Jewish Ghetto and try Carciofi alla Giudia (fried artichokes), a local specialty. Visit Piazza del Campidoglio, designed by Michelangelo, before enjoying a final Roman espresso at a local café. In the afternoon, take a high-speed train to Florence (1.5 hours), check into your hotel, and enjoy a relaxed evening indulging in Tuscan cuisine at a traditional osteria.
Day 4-6: Florence – The Cradle of the Renaissance
Day 4: Art and History
Begin your day at the Accademia Gallery, home to Michelangelo’s world-renowned David statue. Next, explore the Duomo Complex, including the Cathedral of Santa Maria del Fiore, Giotto’s Bell Tower, and Brunelleschi’s Dome, where you can climb to the top for stunning views of Florence. After a light lunch, stroll across the Ponte Vecchio, Florence’s iconic medieval bridge lined with charming jewelry shops. Spend the afternoon at the Uffizi Gallery, one of the world’s most famous art museums, where you can admire masterpieces by Botticelli, Da Vinci, and Caravaggio. End the day with dinner at a rooftop restaurant overlooking the Arno River.
Day 5: Tuscan Escape to Chianti or Pisa
Escape the city and explore the picturesque Tuscan countryside. If you opt for a Chianti wine tour, visit vineyards and enjoy wine tastings accompanied by a traditional Tuscan lunch in a charming villa. Alternatively, take a train to Pisa and see the famous Leaning Tower before continuing to Lucca, a hidden gem with medieval walls, quaint streets, and excellent local cuisine.
Day 6: Local Markets & Train to Venice
Spend the morning visiting Mercato Centrale, a lively market where you can taste fresh local produce, cheese, and wine. Walk up to Piazzale Michelangelo, a panoramic viewpoint offering one of the best views of Florence. In the afternoon, board a high-speed train to Venice (2 hours), check into your hotel, and enjoy a romantic evening stroll along the canals, perhaps stopping for a traditional Venetian cicchetti and a glass of prosecco.
Day 7-8: Venice – The City of Canals
Day 7: Exploring the Floating City
Begin your day at Piazza San Marco, Venice’s most famous square, and visit St. Mark’s Basilica, where you can admire its golden mosaics. Next, explore the opulent Doge’s Palace, walking across the Bridge of Sighs, which once led prisoners to their cells. In the afternoon, take a Gondola ride through Venice’s enchanting canals and explore the Rialto Bridge and its lively market, where you can sample fresh seafood. End the evening with dinner at a canal-side restaurant, enjoying Venetian specialties like Sarde in Saor (sweet and sour sardines).
Day 8: Murano, Burano & Lido
Embark on a boat tour to explore Venice’s nearby islands. Visit Murano, famous for its glass-blowing factories, and watch artisans create intricate glass masterpieces. Continue to Burano, a colorful fishing village known for its lace-making traditions and picturesque streets. If time permits, unwind on the serene beaches of Lido, an elegant escape from Venice’s bustling crowds. Return to Venice in the evening and relax with a spritz at a cozy wine bar.
Day 9-10: Milan – Italy’s Fashion Capital
Day 9: Arrival & Cultural Landmarks
Travel to Milan via high-speed train (2.5 hours) and check into your hotel. Begin exploring at the Duomo di Milano, an architectural marvel with its intricate spires and rooftop terrace offering breathtaking city views. Walk through the Galleria Vittorio Emanuele II, Italy’s oldest shopping gallery, before visiting the legendary Teatro alla Scala, one of the world’s most prestigious opera houses. Enjoy an upscale dinner at a Michelin-starred restaurant to experience Milan’s renowned culinary scene.
Day 10: Art & Shopping Before Departure
On your final day, visit Santa Maria delle Grazie to admire Leonardo da Vinci’s masterpiece, The Last Supper. Spend the rest of the morning exploring the artistic and bohemian Brera District, known for its charming streets and stylish boutiques. In the afternoon, indulge in some last-minute shopping at Via Montenapoleone, Milan’s luxury fashion street, before transferring to Milan Malpensa Airport (MXP) for your departure.
This 10-day Italy itinerary perfectly blends history, culture, gastronomy, and breathtaking scenery. With a mix of world-famous landmarks and hidden gems, you’ll leave Italy with unforgettable memories and a deep appreciation for its timeless charm. Whether you’re savoring pasta in Rome, admiring Renaissance art in Florence, gliding through Venice’s canals, or indulging in Milanese fashion, Italy will captivate you at every turn.
Buon viaggio!
